HPLC Column, Ultra Axis C18, 5um, 4.6mm ID x 150mm Length, 80A. Cogent Brand. 1 EA.
Additional Info:
The 59035‑15P Cogent Ultra Axis C18™ HPLC Column is a high surface area C18 stationary phase, engineered for enhanced retention and selectivity in reversed‑phase chromatography.
This column features a fully double end‑capped C18 bonded phase on high‑purity silica with an 80 Å pore size, making it ideal for USP L1 methods that specifically require 80 Å pore structure.
✅ Widely used as a reliable alternate column in USP methods requiring L1 classification with 80 Å pore size
150 mm Length – High Resolution for Analytical Methods
Provides increased resolving power vs shorter columns
Improves separation of closely related compounds
Increases peak capacity for complex mixtures
Ideal for method development and validation workflows
✅ Selected when resolution and reproducibility are critical
4.6 mm ID – Standard Analytical Platform
Compatible with standard HPLC systems
Ideal for:
routine QC analysis
method validation and transfer
Typical Flow Rate Range
~0.8–1.5 mL/min
✅ Ensures robust, reproducible analytical performance
5 µm Particle – Balanced Efficiency & Durability
Provides:
Consistent efficiency for analytical separations
Long column lifetime
Reliable reproducibility
Higher surface area vs standard C18 phases results in:
Increased retention
Altered selectivity profile
✅ Ideal for method optimization and transfer across systems
80 Å Pore Size – USP L1 Method Compatibility
Designed specifically for:
USP L1 methods requiring 80 Å pore size
Provides:
Enhanced interaction with small molecules
Improved performance in traditional reversed‑phase applications
✅ Ensures method compliance and reproducibility in regulated workflows
Why Choose Ultra Axis C18™ Columns
High Surface Area Selectivity
Provides increased retention and unique selectivity
Enhances resolution of hydrophobic compounds
USP Method Flexibility
Fully compatible with USP L1 methods
Suitable for method transfer and validation
Proven Performance
Long‑standing use in analytical laboratories
Known for reliability and consistency
✅ Ideal for regulated workflows requiring validated performance
Application Performance Advantages
Suitable for:
Hydrophobic compounds
Neutral analytes
Long‑chain fatty acids
Provides:
Increased retention vs standard C18 phases
Enhanced separation of non‑polar analytes
✅ Ideal for reversed‑phase analytical workflows requiring strong retention
System & Sample Considerations
Compatible with standard HPLC systems
Suitable for routine analytical and QC workflows
Recommended sample preparation:
👉 Use 0.2 µm syringe filters for proper sample preparation before injection
✅ Helps:
Prevent column fouling
Maintain long‑term performance and reproducibility
Typical Applications
USP L1 analytical methods
Pharmaceutical QC and validation
Hydrophobic compound separations
Long‑chain fatty acid analysis
Method development and transfer
Routine HPLC analysis
Important Usage Notes
Designed for standard analytical HPLC systems (4.6 mm ID)
Optimized for 80 Å pore size USP L1 methods
Ideal for high‑resolution analytical workflows
Monitor system pressure based on instrument specifications